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Genetics, Health Care and Public Policy基因、卫生保健和公共政策：公共卫生基因导论书籍详细信息
- ISBN：9780521529075
- 作者：暂无作者
- 出版社：暂无出版社
- 出版时间：2007-06
- 页数：334
- 价格：556.20
- 纸张：胶版纸
- 装帧：平装
- 开本：16开
- 语言：未知
- 丛书：暂无丛书
- TAG：暂无
- 豆瓣评分：暂无豆瓣评分
内容简介：
Genetics，Health Care and Public Policy is an introduction to the new discipline of public health genetics。It brings together the insights of genetic and molecular science as a means of protecting and improving the health of the population。Its scope is wide and requires an understanding of genetics，epidemiology，public health and the principles of ethics，law and the social sciences。This book sets out the basic principles of public health genetics for a wide audience from those providing health care to those involved in establishing policy。The emphasis throughout the text is on providing an accessible introduction to the field。The content moves from the basic concepts，including definitions and history，through chapters on genetics，genetic technology，epidemiology，genetics in medicine，genetics in health services，ethical，legal and social implications，to the implications for health policy。It provides one-stop，introductory coverage of this rapidly developing and multidisciplinary field。
书籍目录：
Foreword
Acknowledgements
1 Introduction
The definition of public health genetics
Genetic and environmental factors as determinants of health
Genetic disease，complex disease and the combined effects of
genetic and environmental factors
The emergence and development of public health genetics
Advances in epidemiology and its application to public health
The rise of genetic epidemiology
The growth of genetic science
The impetus for public health genetics
Community genetics
Attitudes to public health genetics
An international public health genetics network：the Bellagio initiative
About this book
Further reading and resources
Principles of public health
The emergence of public health genetics
The human genome project and‘genomic medicine’
Community genetics
Current developments in public health genetics
Genomics and global health
2 Genetic science and technology
Basic molecular genetics
Genes and the genome
Chromosomas
The‘central dogma’：DNA makes RNA makes Drotein
Gene structure and expression in more detail
The complexity of the genetic programme
Genetic variation：mutation and polymorphism
Cell division and the maintenance of the genome
Miosis and recombination：the formation 0f sex cells
Inheritance patterns
Genes and disease
Mendelian(‘single—gene’)diseases
Mitochondrial disorders
Chromosomal disorders
Diseases caused by disorders in epigenetic mechanisms
Mendelian subsets of common diseases
MultifactoriaI disease
Cancer
Some complexities of the relationship between genes and djsease
Penetrance
Inherited and new mutations
Genetic heterogeneity
Variable expressivity
Genetic technology
Cutting and joining pieces of DNA
Separating pieces of DNA in a mixture
Detecting specific sequences：hybridisation
Fluorescent in situ hybridisation(FISHl
DNA cloning and clone libraries
The polymerase chain reaction
DNA sequencing
DNA microarrays
Markers and maps
The human genome project
Mapping human genetic variation：SNPs and haplotypes
The post—genome challenge
Identifying genes and studying gene function
Proteomics
Comparative genomics
Bioinformatics
Systems biology
Epidemiological and biomedical informatics
……
3 Fundamentals of genetic epidemiology
4 Genetics in medicine
5 Genetics in health services
6 Ethical，legal and social implications of genetics
7 Policy implications
Index
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书籍介绍
Genetics, Health Care and Public Policy is an introduction to the new discipline of public health genetics. It brings together the insights of genetic and molecular science as a means of protecting and improving the health of the population. This book sets out the basic principles of public health genetics for a wide audience of readers from those providing health care to those involved in establishing health policy. It provides one-stop introductory coverage of this rapidly developing and multidisciplinary field.
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